We have replaced the batteries multiple times, even checking the voltage coming out. The only fix does seem to be rebooting the computer. We also have problems with the tv signal needing to be very good for the tuner to register. We have a converter box on another tv and it picks up the signals much better than the touchsmart.

Sounds more like a software problem or a conflict with the Win Media Center software since it always clears on reboot. Any particular programs running in the background in seperate windows? Does it do it when others are logged on to their respective accounts? If there is no one else's account, create a new one and log off or reboot completely, then login as the new user with admin priveleges to see if it acts up when you are in a differently set up account. What AntiVirus do you use? Any extra Internet Security programs in addition to Windows or Defender? You really only want to run one of each, AV and ISec, no more, or really weird things start to happen and not happen.
Dave